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One-pot multi-enzymatic production of purine derivatives with application in pharmaceutical and food industry
(Catalysts, 2018)
Biocatalysis reproduce nature’s synthetic strategies in order to synthesize different organic
compounds. Natural metabolic pathways usually involve complex networks to support cellular
growth and survival. In this regard, ...
Enzymatic production of dietary nucleotides from low-soluble purine bases by an efficient, thermostable and alkali-tolerant biocatalyst
(Food Chemistry, 2017-03-28)
Traditionally, enzymatic synthesis of nucleoside-5′-monophosphates (5′-NMPs) using low water-soluble purine bases has been described as less efficient due to their low solubility in aqueous media. The use of enzymes from ...
One-pot, one-step production of dietary nucleotides by magnetic biocatalysts
(Catalysts, 2018-04-27)
The enzymatic synthesis of nucleotides offers several advantages over traditional multistep chemical methods, such as stereoselectivity, regioselectivity, enantioselectivity, simple downstream processing, and the use of ...
Cloning, expression and biochemical characterization of xanthine and adenine phosphoribosyltransferases from thermus thermophilus Hb8
(Biocatalysis And Biotransformation, 2018-05-04)
Purine phosphoribosyltransferases, purine PRTs, are essential enzymes in the purine salvage pathway of living organisms. They are involved in the formation of C-N glycosidic bonds in purine nucleosides-5′-monophosphate ...