Mostrando ítems 1-4 de 4

Actinic keratosis in Colombia: first approaches

Castillo Molina, David; Fierro Lozada, Jesus Daniel; Quintero Estupiñan, Diana; Carroll Patiño , María Juliana; Reyes Rey, Mariana; Chacón Jaramillo, Paula A.; Ramírez Herrera, Nanis; Rubiano Mojica, Paula Celeste; ALVIS-ZAKZUK, NELSON J.; Bula Galán, Gabriela; Castillo Saavedra, David E. (Mosby Inc.United States, 2021-09-01)

Introduction: Actinic keratoses (AK) are preneoplastic lesions secondary to chronic sun exposure, whose risk of becoming malignancy is greater than 20%. Prevalence studies of AK are uncommon. Here we describe clinical and ...
Cryotherapy as an adjuvant in the treatment with vismodegib for local advanced nonsurgical basal cell carcinoma: a report of 8 cases

Castillo Molina, David; Fierro Lozada, Jesus Daniel; García C., Ana María; Molano Pérez, Manuela Alejandra; Cantillo Avilez, Melissa; Guerrero Roncancio, Laura; Muñoz-Ordoñez, Sara; Campo Slebi, Isabella; ALVIS-ZAKZUK, NELSON J.; Castillo Saavedra, David E.; Martinez Zuñiga, Diego M. (Mosby Inc.United States, 2021-09-01)

Introduction: Basal cell carcinoma (BCC) is the most prevalent skin cancer worldwide. The most frequently used treatment for BCC is surgical resection. Lately, there are other options for nonsurgical BCC such as hedgehog ...
Exacerbation and appearance of dermatosis during COVID-19 quarantine period in Bogotá, Colombia: a descriptive study of the psychological impairments

Castillo Molina, David; Fierro Lozada, Jesus Daniel; Camacho-Lazaro, Luisa F.; Reyes Rey, Mariana; Molina Dorado, Daniela M.; Polania Tovar, Maria Daniela; Chacon Jaramillo , Paula Andrea; Sánchez Zapata, Maria Juliana; ALVIS-ZAKZUK, NELSON J.; Cantillo, Diana P. (Mosby Inc.United States, 2021-09-01)

Introduction: Quarantine established in several countries by the new coronavirus pandemic, dramatically changed our lifestyle, affecting quality of life, skin, and psyche. We described the skin diseases that initiated or ...
Health-related quality of life (HRQoL) in patients with hidradenitis suppurativa: a single center analysis

Castillo Molina, David; Chacón Jaramillo, Paula A.; Duran-Torres, Marcela; Fierro Lozada, Jesus Daniel; Molina Dorado, Daniela M.; Polania Tovar, Maria Daniela; Carroll Patiño , María Juliana; Vargas Caycedo, Zamira P.; ALVIS-ZAKZUK, NELSON J. (Mosby Inc.United States, 2021-09-01)

Introduction: Hidradenitis suppurativa (HS) is an underdiagnosed and undertreated skin affection. Previous studies suggest that psychiatric conditions are more frequent in patients with HS than in other dermotologic diseases. ...

Envíos recientes

Actinic keratosis in Colombia: first approaches
...
Castillo Molina, David | 2021-09-01

Introduction: Actinic keratoses (AK) are preneoplastic lesions secondary to chronic sun exposure, whose risk of becoming malignancy is greater than 20%. Prevalence studies of AK are uncommon. Here we describe clinical and epidemiologic characteristics of patients with AK assessed in a dermatology center from Bogota, Colombia. Materials and methods: A descriptive retrospective study was performed. Data were collected from January 2014 to July 2020. These included age at diagnosis, sex, occupation according sun exposure (inside-job, outside-job and inside/outside-job), dwelling place, Fitzpatrick phototype, anatomical location, progression time, skin cancer (SC) history and development. We used relative and absolute frequencies to describe patients. Data analysis was performed in Epi Info. Results: Of 820 patients, 61% were women. Mean age was 66 years (SD ± 12). Of all patients, 5.4 out of 10 were phototype III. The median progression time was 34 months. The 57% (n = 468) of patients had inside-jobs. The face was the most commonly affected area in 750 patients (91%). History of SC was observed in 27% of patients, and 2.56% (n = 21) developed SC, from which five cases were squamous cell carcinoma. Conclusion: Actinic keratosis may evolve into SC in a considerable percentage conversely to our study. We found that most of the patients with AK had an inside-job, which might reinforce the impact of genetic load, artificial lights exposure and the effect of protection barriers on AK development. Further studies are needed to improve clinical characteristics knowledge associated with AK.

LEER
Cryotherapy as an adjuvant in the treatment with vismodegib for local advanced nonsurgical basal cell carcinoma: a report of 8 cases
...
Castillo Molina, David | 2021-09-01

Introduction: Basal cell carcinoma (BCC) is the most prevalent skin cancer worldwide. The most frequently used treatment for BCC is surgical resection. Lately, there are other options for nonsurgical BCC such as hedgehog pathways inhibitors, which is indicated in patients whose cancer is locally advanced and unresectable. We described the response of patients treated with vismodegib and cryotherapy as adjuvant management. Materials and methods: We conducted an observational retrospective study in a dermatologic center in Bogota, Colombia. We included patients with BCC diagnosis and were treated with vismodegib and cryotherapy from January 2018 to August 2020. Variables included age, sex, phototype, lesion location, treatment duration, number of cryotherapies, months of follow-up, and histologic subtypes. Variables were analyzed using Microsoft Excel 2016. Results: Of eight patients reviewed, four were female. Median age was 70 years old. Photoype III was the most frequent. Zone H was the most affected location. The mean number of cryotherapy sessions received during vismodegib treatment was 4.75, and the mean duration of treatment with the hedgehog inhibitor was 3.5 months. Patients were followed up for 15.57 months. Of the eight patients, four presented nodular pattern histology, in the rest the mixed subtype predominated. Conclusion: In general, there was a good response to treatment with a notable decrease in the size and control of the lesions. No side effects were described during the follow-up time; however, the patients will continue to be under strict controls.

LEER
Exacerbation and appearance of dermatosis during COVID-19 quarantine period in Bogotá, Colombia: a descriptive study of the psychological impairments
...
Castillo Molina, David | 2021-09-01

Introduction: Quarantine established in several countries by the new coronavirus pandemic, dramatically changed our lifestyle, affecting quality of life, skin, and psyche. We described the skin diseases that initiated or were exacerbated in quarantine and assessed the impact on quality of life and the possible presence of anxiety. Materials and methods: We performed a descriptive study from April 2020 to August 2020, assessing two questionnaires: Dermatology Life Quality Index (DLQI) and Hospital Anxiety and Depression Scale (HADS-A) in a dermatologic center. Variables analyzed were age, sex, onset or exacerbation of skin disease, DLQI and HADS-A scores. We used relative and absolute frequencies to describe patients. We collected data using Microsoft Excel and analyzed with SPSS. Results: Of 124 patients, 85 (69%) were women. Acne was the most frequent dermatosis with 18,5% (n = 23), followed by contact dermatitis with 22 patients (17,7%). HADS-A results showed that 24.2% of patients had psychological distress. DLQI most frequent results had a small effect in life (29.8%; n = 37). Patients with psoriasis and eczematous diseases showed a major impact on their quality of life. Conclusions: Quarantine has been related to exacerbation of pre-existent dermatologic conditions and the onset of skin affections. Lifestyle changes influenced the occurrence of acne and contact dermatitis. DLQI and HADS results did not show an important impact in patients’ quality of life. Further epidemiologic studies are needed to determine whether there is a causal relationship between quarantine and these dermatologic conditions.

LEER
Health-related quality of life (HRQoL) in patients with hidradenitis suppurativa: a single center analysis
...
Castillo Molina, David | 2021-09-01

Introduction: Hidradenitis suppurativa (HS) is an underdiagnosed and undertreated skin affection. Previous studies suggest that psychiatric conditions are more frequent in patients with HS than in other dermotologic diseases. In Colombia, we found no descriptive studies of its comorbidities. We described the HRQoL in patients with HS and its relationship with some comorbidities. Materials and Methods: We performed a descriptive and retrospective study in patients with HS in a dermotologic center in Bogotá, DC. We analyzed 24 patients attended from January 2017 to August 2020, assessing variables as age, sex, body mass index (BMI), and comorbidities. The dermatology life quality index (DLQI) and Hospital Anxiety and Depression scale (HAD) were applied in 19 patients. Univariate analysis and nonparametric statistics were performed. Data was collected and analyzed in Microsoft Excel 365 and SPSS26. Results: Of 24 patients, 18 were women (75%). The median age was 30 years old (IQR 21). The most frequently found comorbidities were acne and cardiovascular disease, 35.5% and 20.8%, respectively. DLQI’s most frequent result was a very large effect in 26.3% (n = 5). HADS-A showed anxiety in 6 cases (31.6%). HAD-D showed depression in 2 patients (10.5%). Conclusion: We found a greater association with acne and cardiovascular disease, which suggests a systemic and inflammatory involvement of the disease. Our findings related to HADS-A and DLQI reveal a great impact on the HRQoL and existence of anxiety symptoms, reinforcing the importance of multidisciplinary management. Further, larger studies are needed to validate these findings.

LEER

Listar por eissn "1097-6787"

Actinic keratosis in Colombia: first approaches ﻿

Cryotherapy as an adjuvant in the treatment with vismodegib for local advanced nonsurgical basal cell carcinoma: a report of 8 cases ﻿

Exacerbation and appearance of dermatosis during COVID-19 quarantine period in Bogotá, Colombia: a descriptive study of the psychological impairments ﻿

Health-related quality of life (HRQoL) in patients with hidradenitis suppurativa: a single center analysis ﻿

Envíos recientes

Actinic keratosis in Colombia: first approaches

Cryotherapy as an adjuvant in the treatment with vismodegib for local advanced nonsurgical basal cell carcinoma: a report of 8 cases

Exacerbation and appearance of dermatosis during COVID-19 quarantine period in Bogotá, Colombia: a descriptive study of the psychological impairments

Health-related quality of life (HRQoL) in patients with hidradenitis suppurativa: a single center analysis

Actinic keratosis in Colombia: first approaches

Cryotherapy as an adjuvant in the treatment with vismodegib for local advanced nonsurgical basal cell carcinoma: a report of 8 cases

Exacerbation and appearance of dermatosis during COVID-19 quarantine period in Bogotá, Colombia: a descriptive study of the psychological impairments

Health-related quality of life (HRQoL) in patients with hidradenitis suppurativa: a single center analysis