Listar por tema "Nucleosides"
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Biotechnological and biomedical applications of enzymes involved in the synthesis of nucleosides and nucleotides
(Corporación Universidad de la Costa, 2021-08-03)Nucleic acid derivatives are involved in cell growth and replication, but they are also particularly important as building blocks for RNA and DNA synthesis. In nature, purine and pyrimidine nucleotides are synthesized ... -
N-Ribosyltransferase From Archaeoglobus veneficus: A Novel Halotolerant and Thermostable Biocatalyst for the Synthesis of Purine Ribonucleoside Analogs
(Frontiers in Bioengineering and Biotechnology, 2020-06-20)Nucleoside-2′-deoxyribosyl-transferases (NDTs) catalyze a transglycosylation reaction consisting of the exchange of the 2′-deoxyribose moiety between a purine and/or pyrimidine nucleoside and a purine and/or pyrimidine ... -
Purine and pyrimidine phosphoribosyltransferases: A versatile tool for enzymatic synthesis of nucleoside-5′-monophosphates
(Current Pharmaceutical Design, 2017)ackground: In recent years, enzymatic methods have shown to be an efficient and sustainable alternative for the synthesis of nucleosides and nucleoside-5′-monophosphates (NMPs) to the traditional multistep chemical methods, ...