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dc.contributor.authorPerachi Nordin, Adrianespa
dc.contributor.authorDa Silva, Julianaspa
dc.contributor.authorTelles De Souza, Claudiaspa
dc.contributor.authorNiekraszewiczl Boufleur, Liana Appespa
dc.contributor.authorFerraz Dias, Johnnyspa
dc.contributor.authorDa Boit Martinello, Katiaspa
dc.contributor.authorSilva Oliveira, Marcos Leandrospa
dc.contributor.authorGrivicich, Ivanaspa
dc.contributor.authorGarcia Hilario, Ana Leticiaspa
dc.contributor.authorSilva Oliveira, Luis Felipespa
dc.contributor.authorDa Silva Rabaioli, Fernandaspa
dc.date.accessioned2018-11-21T00:12:09Z
dc.date.available2018-11-21T00:12:09Z
dc.date.issued2018-03
dc.identifier.issn03043894spa
dc.identifier.urihttp://hdl.handle.net/11323/1573spa
dc.description.abstractCoal processing generates a large volume of waste that can damage human health and the environment. Often these wastes produce acid drainage in which several minerals are crystallized (evaporites). This study aimed to identify secondary minerals, as well as the genotoxic potential of these materials. The samples were collected at two sites along the Rocinha River in Santa Catarina state (Brazil): (1) directly from the source of the acid drainage (evaporite 1), and (2) on the river bank (evaporite 2). The samples were characterized by X-ray diffraction and by particle-induced X-ray emission techniques. In vitro genotoxicity testing using Comet assay and Micronucleus test in V79 cells was used to evaluate evaporite samples. Our study also used System Biology tools to provide insight regarding the influence of this exposure on DNA damage in cells. The results showed that the samples induced DNA damage for both evaporites that can be explained by high concentrations of chromium, iron, nickel, copper and zinc in these materials. Thus, this study is very important due to the dearth of knowledge regarding the toxicity of evaporites in the environment. The genetic toxicity of this material can be induced by increased oxidative stress and DNA repair inhibition.spa
dc.language.isoeng
dc.publisherJournal Of Hazardous Materialsspa
dc.rightsAtribución – No comercial – Compartir igualspa
dc.subjectCoal Mine Drainageeng
dc.subjectComet Assayeng
dc.subjectEvaporiteeng
dc.subjectMicronucleus Testeng
dc.subjectSystem Biologyeng
dc.titleIn vitro genotoxic effect of secondary minerals crystallized in rocks from coal mine drainageeng
dc.typeArtículo de revistaspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.identifier.doihttps://doi.org/10.1016/j.jhazmat.2017.12.026spa
dc.identifier.instnameCorporación Universidad de la Costaspa
dc.identifier.reponameREDICUC - Repositorio CUCspa
dc.identifier.repourlhttps://repositorio.cuc.edu.co/spa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa


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