Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
Artículo de revista
2019-11-13
International Journal of Molecular Sciences
The complex physiology of eukaryotic cells is regulated through numerous mechanisms,
including epigenetic changes and posttranslational modifications. The wide-ranging diversity of these mechanisms constitutes a way of dynamic regulation of the functionality of proteins, their activity, and their subcellular localization as well as modulation of the di erential expression of genes in response to external and internal stimuli that allow an organism to respond or adapt to accordingly. However, alterations in these mechanisms have been evidenced in several autoimmune diseases, including systemic lupus erythematosus (SLE). The present review aims to provide an approach to the current knowledge of the implications of these mechanisms in SLE pathophysiology.
- Artículos científicos [3154]
Descripción:
Epigenetic Mechanisms and Posttranslational.pdf
Título: Epigenetic Mechanisms and Posttranslational.pdf
Tamaño: 627.7Kb
PDFLEER EN FLIP
Título: Epigenetic Mechanisms and Posttranslational.pdf
Tamaño: 627.7Kb
PDFLEER EN FLIP
Os arquivos de licença a seguir estão associados a este item: